FREQUENCY OF IL 12B GENE POLYMORPHISM AMONG PATIENTS WITH CHRONIC RHINOSINUSITIS POLYPOSIS
Keywords:
paranasal sinuses, polyp, allele, genotypingAbstract
Analyzing the prevalence of genotypic variants of this polymorphism, we revealed a direct association of the C/C monogenotype of the A1188C rs3212227 polymorphism in the IL12B gene with the development of polyposis processes. In addition, these data emphasize the prognostic significance of the C/C genotype of the rs1800896 polymorphism of the IL-12B gene in the development of CPMS. In carriers of this genotype, the relative risk of developing CPMS increases by more than 3 times, compared with carriers of other genotypic variants of the rs3212227 polymorphism of the IL12B gene.
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Published
2023-06-02
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Ulugbek S. Khasanov, Ulugbek N. Vokhidov, & Jamolbek A. Djuraev. (2023). FREQUENCY OF IL 12B GENE POLYMORPHISM AMONG PATIENTS WITH CHRONIC RHINOSINUSITIS POLYPOSIS. Central Asian Journal of Medicine, (3), 5-15. Retrieved from https://mail.journals.tma.uz/index.php/cajm/article/view/497
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