JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE

SCIENCE AND TECHNOLOGY IN THE UNITED STATES

2025-01-13T18:01:32+00:00

Science and technology in the United States has a long history, producing many important figures and developments in the field. The United States of America came into being around the Age of Enlightenment (1685 to 1815), an era in Western philosophy in which writers and thinkers, rejecting the perceived superstitions of the past, instead chose to emphasize the intellectual, scientific and cultural life, centered upon the 18th century, in which reason was advocated as the primary source for legitimacy and authority. Enlightenment philosophers envisioned a "republic of science," where ideas would be exchanged freely, and useful knowledge would improve the lot of all citizens. The United States Constitution itself reflects the desire to encourage scientific creativity. It gives the United States Congress the power "to promote the progress of science and useful arts, by securing for limited times to authors and inventors the exclusive right to their respective writings and discoveries". This clause formed the basis for the U.S. patent and copyright systems, whereby creators of original art and technology would get a government granted monopoly, which after a limited period would become free to all citizens, thereby enriching the public domain.

We continue to acquaint you with interesting facts and historical information regarding great scientific discoveries and achievements, as well as educational processes in leading foreign universities. The next article is a continuation of our previous publications.

THE PROBLEM OF DIAGNOSIS AND TREATMENT OF NECROTIZING SOFT TISSUE INFECTIONS IN PATIENTS WITH DIABETES MELLITUS

2025-01-10T10:25:25+00:00

Necrotizing soft tissue infections have been known for millennia and continue to impose a significant burden on both patients and society in terms of morbidity, mortality and resource allocation. While it was once categorized as a rare disease, its incidence has been increasing in recent years, especially in patients with diabetes mellitus. The manifestation of the disease can vary from a lightning-like manifestation to barely noticeable and insidious development. A significant proportion are patients with late complications of surgical infections of soft tissues, the treatment of which presents certain difficulties. The basic principles of diagnosis, rapid and broad antimicrobial therapy, and aggressive sanitation have remained unchanged, but the increasing incidence suggests that new diagnostic and treatment methods are needed to combat this deadly disease. This review highlights the basic principles of diagnosis and management of necrotizing soft tissue infections. The review provides the historical context, etiology, pathogenesis and diagnosis of the disease, emphasizing the problem of early diagnosis.

CLINICAL AND IMMUNOLOGICAL ASPECTS OF PROGNOSIS OF PURULENT-INFLAMMATORY COMPLICATIONS OF ULCERATIVE COLITIS

2025-01-13T08:15:00+00:00

Background. Over the past fifty years, there has been a steady increase in the prevalence of diabetes mellitus all over the world. This trend remains very characteristic of industrialized countries, where, along with coronary heart disease, obesity and metabolic syndrome, diabetes mellitus is registered from 5% to 10%. The problem of treating purulent diseases of soft tissues, remaining relevant throughout the history of mankind, under conditions of a high incidence of diabetes mellitus, is becoming more and more important both clinically and socially.

Material and methods. The object of the study was the data of a comprehensive examination and treatment of 123 patients with wound infection complicated by sepsis against the background of diabetes mellitus from 2011 to 2022. The subject of the study was: general and local clinical status of patients, laboratory blood parameters, including cytokine profile, predictors of inflammatory response, morphometric impressions of the wound, biopsionic material of the wound, wound exudate. In the dissertation, clinical, immunological, hematological, biochemical, morphological, microbiological, planimetric and statistical research methods were used.

Result. It has been proved that the use of the method developed by us for diagnosing the phase of the wound process complicated by sepsis in patients with diabetes mellitus makes it possible to increase the probability of diagnosing the development of generalization of the inflammatory process and to determine the option of using the method of treating wound infection.

Conclusion. The introduction of a new therapeutic and diagnostic algorithm for the local treatment of wound infection complicated by sepsis in patients with diabetes mellitus, developed by us, made it possible to increase the number of good and satisfactory treatment results, reduce the number of cases with unsatisfactory treatment results and avoid cases with fatal outcomes in the main group of patients.

DIFFERENTIATED APPROACHES TO THE TREATMENT OF SURGICAL INFECTION OF SOFT TISSUES COMPLICATED BY SEPSIS IN THE BACKGROUND OF DIABETES MELLITUS

2025-01-13T10:55:36+00:00

DIFFERENTIATED TREATMENT OF DIABETIC FOOT SYNDROME IN PATIENTS WHO HAVE HAD COVID-19

2025-01-13T09:47:42+00:00

Diabetic foot syndrome is the most common complication of diabetes mellitus, since both angiopathy and neuropathy are a component of this pathology. In patients who have had COVID-19, diabetic foot syndrome proceeds in a more aggressive form, characterized by an increase in necrobiotic processes, even if the patency of the vessels of the lower extremities is restored. In this work, we tried to show the main clinical and laboratory signs of the onset and course of diabetic foot syndrome in patients who have had COVID-19.