https://mail.journals.tma.uz/index.php/jesm/issue/feed 2026-01-26T22:21:30+00:00 Alisher Oripovich Okhunov general-surgery@mail.ru Open Journal Systems <p>"Journal of Education and Scientific Medicine" Scientific peer-reviwed journal of Tashkent State Medical University</p> https://mail.journals.tma.uz/index.php/jesm/article/view/1501 2026-01-26T21:08:32+00:00 A.O. Okhunov general-surgery@mail.ru

<div><span lang="">The high incidence of acute commissural small bowel obstruction and its complications in elderly patients is accompanied by an increase in postoperative mortality, which is based on immune system disorders. We set ourselves the goal of determining the degree of cytokinemia development in patients with various forms of abdominal adhesions. At the same time, among the analyzed cohorts of patients, we also identified patients with acute adhesions, small intestinal obstruction and a form complicated by peritonitis. In the blood of patients, we study the concentration of interleukins, which belong to the group of pro-inflammatory. We found that changes in the concentration of interleukins in the blood depend on the pathology being analyzed, related to intestinal obstruction or the development of peritonitis. </span></div>

2026-01-26T00:00:00+00:00 Copyright (c) 2026 JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE https://mail.journals.tma.uz/index.php/jesm/article/view/1502 2026-01-26T22:21:30+00:00 F.M. Abdurakhmanov sardorruss@mail.ru

<div>From the very first report of mass mortality among diabetic patients infected with COVID-19 infection, emphasis was placed on the severity of damage to the respiratory system in the form of acute respiratory distress syndrome in adults. The unifying factor in the pathogenesis of such a fatal change was the development of dysfunction of the endothelial system (DES), which leads not only to systemic inflammatory damage to the vascular endothelium but also to its consequences in the form of increased blood clotting and a decrease in fibrinolysis processes. The changes that occur in the body of patients after COVID-19 do not disappear completely. First of all, this should be noted about patients with chronic morbid backgrounds, such as, for example, type 2 diabetes mellitus (T2DM). In our study, endothelial function conditions were evaluated in 92 patients who have T2DM. Three cohorts of patients were organized. Indicators characterizing the state of DES were examined in blood obtained by puncture from a peripheral vein.</div>

2026-01-26T00:00:00+00:00 Copyright (c) 2026 JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE