COMPARATIVE ASSESSMENT OF THE IMMUNE STATUS OF PATIENTS WITH DIABETIC FOOT SYNDROME IN CRITICAL LOWER LIMB ISCHEMIA

Authors

  • N.A. Nuraliev Bukhara State Medical Institute
  • B.Z. Khamdamov Bukhara State Medical Institute

Keywords:

diabetic foot syndrome, critical lower limb ischemia, early diagnosis, cytokine status.

Abstract

Objective: To study the indicators of the immune system of patients with diabetic foot syndrome (SDS) with signs of critical
lower limb ischemia (CINC). Material and methods: 412 patients with diabetic foot syndrome with signs of CINC were monitored,
of which 283 (68.7%) were men and 129 (31.3%) were women. Moreover, all examined had a systemic inflammatory response
syndrome. 99 patients were urban residents (24.0%), 313 people lived in rural areas (76.0%). The average age of the examined is
62.2 years. The control group consisted of 30 healthy individuals of comparable gender and age. Results: A comparative analysis of
the cytokine status in patients with SDS with signs of CINC and healthy individuals showed that the level of both cytokines (IL-17A
and IL-10) in patients significantly exceeded the control values, and the trend and direction of changes were the same. Conclusions:
The definition of IL-17A has great diagnostic value as an additional test for early diagnosis of complications in patients with diabetes
mellitus with signs of CINC.

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Published

2020-07-08

How to Cite

Nuraliev, N., & Khamdamov, B. (2020). COMPARATIVE ASSESSMENT OF THE IMMUNE STATUS OF PATIENTS WITH DIABETIC FOOT SYNDROME IN CRITICAL LOWER LIMB ISCHEMIA. Toshkent Tibbiyot Akademiyasi Axborotnomasi, (1), 132-137. Retrieved from https://mail.journals.tma.uz/index.php/ttaa/article/view/31

Issue

Section

Clinical Medicine