TREATMENT OF PATIENTS WITH ACUTE DESTRUCTIVE PANCREATITIS USING EXTRACORPOREAL DETOXIFICATION METHODS

Abstract

assessment of the effectiveness of extracorporeal detoxification methods in the treatment of patients
with severe acute destructive pancreatitis. Material and methods: the study included 84 patients with destructive
pancreatitis who were treated at the clinic of faculty surgery of the Peoples’ Friendship University of Russia at the
base of the city clinical hospital named after V.V. Vinogradova (Moscow), aged 18 to 80 years. Men 66 (78.6%), women
18 (21.4%). Results: 29 patients died, the overall mortality rate was 34.5%. Among the patients of the 1st group
who underwent extracorporeal treatment methods, due to PON with the addition of pneumonia, sepsis, arrosive
bleeding, retroperitoneal phlegmon died 12 (24%), the treatment duration was 35 ± 4 days. In the 2nd group, due
to PON with the addition of pneumonia, sepsis, arrosive bleeding, retroperitoneal phlegmon, abscess of the omental
bursa, pancreatogenic shock, the lethal outcome occurred in 17 (50%), the duration of treatment was 19 ± 1.5 days.
Conclusions: earlier the use of extracorporeal detoxification methods for destructive pancreatitis leads to a decrease
in mortality of patients in hospital. Extracorporeal detoxification methods for destructive pancreatitis can be used in
operated and non-operated patients.