Toshkent tibbiyot akademiyasi axborotnomasi

THE EFFECT OF DITERPENIC ALKALOIDS OF ZONGORIN AND 1-O-BENZOYLNAPEPELLIN ON THE CONTRACTILE ACTIVITY OF THE SMOOTH MUSCLES OF THE RAT AORTA

A.T. Esimbetov — 2020-07-16

COMPARATIVE EVALUATION OF HEPATOPROTECTIVE EFFECTS OF KATACIN AND GERANIL ON A MODEL OF ACUTE TOXIC LIVER DAMAGE

Z.A. Khushbaktova — 2020-07-16

to evaluate the effectiveness of new domestic drugs (cavergal, geranyl and catacin) in the correction of the
main hepatic syndromes: cytolysis, cholestasis, mesenchymal inflammation and hepatocellular insufficiency in a model of
toxic liver damage. Material and methods: studies were conducted on 75 male rats with acute toxic liver damage, which was
reproduced by administering heliotrin at a dose of 200 mg / kg, 8 rats were included into intact group. Biochemical studies
of blood serum were performed on a biochemical analyzer. Results: experimental pharmacotherapy of acute toxic liver
damage with new drugs katatsin and geranil significantly reduced rates of cytolysis, cholestasis, mesenchymal inflammation.
The preparations increased the protein synthesis function of the liver. According to hepatoprotective properties, catacin and
geranil were not inferior to Karsil to the hepatoprotector and significantly outperformed the antihypoxant of the cavergal.
Conclusion: the plant flavonoids catacin and geranyl have pronounced hepatoprotective properties.

EPIDEMIOLOGY OF HELMINTHOSIS IN CHILDREN WITH ANEMIA

O.A. Kuliev — 2020-07-16

The article presents data on the prevalence, the main ways of infection of helminthiases in detectives with
anemia. To date, the spread of parasitic diseases is one of the topical problems of mankind. According to the WHO
(2014), in the world more than two billion people suffer from intestinal parasites. It should be noted that children
of school and younger age are the main group at risk of the disease.

DEVELOPMENT AND IMPLEMENTATION OF THE QUESTIONNAIRE TO DETECT ALLERGIC DISEASES IN CHILDREN

Sh.A. Ibragimova — 2020-07-16

For the first time developed and implemented a questionnaire consisting of 34questions divided into several blocks, which can
be used to evaluate the epidemiology of allergic diseases in children and the risk factors for allergies. The basis of the questionnaire
laid allergic diseases and conditions that are included in ICD-10, and allergic diseases are medical and verified. Profile is designed
to answer the parents or their legal representatives. A survey of 500 parents of firstgraders in 3 schools of the Tashkent region.

FEATURES OF DIABETES MELLITUS IN HIV-INFECTED PATIENTS

B.X. Shagazatova — 2020-07-16

Diabetes mellitus is one of the urgent problems of contemporary medicine, and today it is growing radiply. In diabetes,
the risk of such diseases as lung tube, chronic hepatitis B,C and HIV increases. The increase in the number of HIV-infected
patients and the prolonged life expectancy increase the frequency of joint management of these two diseases.

APPROACH TO BUILDING THE PROCESS OF EMPLOYMENT OF STUDENTS AND GRADUATES OF MEDICAL UNIVERSITIES

A.F. Marasulov — 2020-07-16

The article highlights the main components and problems of building the process of employment of students and
graduates of medical universities. Deficiencies have been identified in the mechanism of employment and employment
monitoring of graduates of medical universities. Ways to eliminate these issues and shortcomings have been identified
based on the creation of “Employment System” a republican systematic online database of graduates of medical
universities. The structural-functional scheme of the automated workplaces of interaction instances and units for the
implementation of the employment process of students and graduates in the “Employment System” was compiled.

LONG-TERM LABOR DURING THE SECOND WORLD WAR EFFECTS ON WORKERS 'HEALTH AND LABOR PRODUCTIVITY

2020-07-16

PHENOMENON OF NATIONAL IDENTIFICATION

L.Yu Maxmudova — 2020-07-16

The answer and thoughts about the set
the question can be found in the works and studies of
Western scholars, philosophers, political scientists such as
B. Anderson, M. Hroh, E. Hobsbaum, E. Smith, E. Gelner,
E. Renan, Yu.V. Bromley, C. Calhoun, C. Levy-Strauss,
J. Derrida, S. Huntington, M. Weber, E. Erickson, O.
Bauer et al.
There are concepts of nation and national;
different theories and points of view regarding
problems of preserving the nation and national
due.

IN THE FORMATION OF A HEALTHY GENERATION SPIRITUALITY THE ROLE OF LEGAL CULTURE AS AN IMPORTANT FACTOR

B.U Ruziev — 2020-07-16

HYGIENIC SIGNIFICANCE OF RISK FACTORS IN DETERMINING THE STRUCTURE OF THE INCIDENCE OF FOOTWEAR WORKERS

F.L. Azizova — 2020-07-16

to study the structure of the incidence of workers shoe production, as well as risk factors affecting the
distribution of diseases in the structure. Material and methods: determined the structure and incidence for 2015-2017.
on the basis of appealability to treatment-and-prophylactic institutions of Fergana footwear production workers. The
analysis of the health status of workers in selected groups (experimental, control) was carried out, where the primary
document was leaflets of temporary disability. Results: the studies conducted in 2015–2017 at the Fergana shoe factory
showed a causal relationship between the effects of sustained indicators of severity and tension, factors of the working
environment, features of professional affiliation and morbidity among workers depending on gender, age, length of
service. The majority of the diseased are women (60%) working in the production workshops, which are the main labor
force in the factory. Conclusions: the incidence with temporary disability over the three years both among working
women and men increased significantly (P <0.05). In the structure of incidence, the first leading places are occupied by:
SARS and influenza (24.0%), diseases of the musculoskeletal system (22.7%), diseases of the connective tissue (19.5%).

HYGIENIC ASSESSMENT OF THE LABOR PROCESS OF WORKERS IN THE SHOE INDUSTRY

F.L Azizova — 2020-07-16

hygienic assessment of the working conditions of employees of shoe production on the basis of determining
the main indicators of the severity of labor and the intensity of the process. Material and methods: studies were conducted
among 41 employees of 4 main workshops of the Fergana shoe production in the dynamics of the working day: before work
began (800 hours); after the lunch break (1100 hours), before the end of the work (1500 hours). Time observations were
conducted in the main professional groups. Results: according to the obtained results, it was found that workers of the shoe
production assigned an average of 65.3 to 80.0% of the working time for the main work, while for auxiliary operations from
7.3% to 23.0%, besides, 6.2% and 1.2% of the time is spent on identifying the causes of technological failures and other
distracting operations. Conclusions: the irrational mode of labor and the distribution of the main technological operations
of production workers, leads to early body fatigue, stagnation in production, reduced productivity of labor.

HEALTH CONDITION OF OLDER PEOPLE AND MEDICAL FOLLOW-UP IN THE PRIMARY HEALTH CARE

D.J. Aniozova — 2020-07-16

to study the morbidity of older people and the provision of primary health care to them in selected
regions of Uzbekistan. Material and methods: selectively in 6 districts of 6 regions of Uzbekistan and in Tashkent city,
a survey (survey) of 365 people 60 years and older living in households was conducted. For the survey used a specially
designed questionnaire; data copying was carried out in the developed clinical map. Results: every second respondent
noted the presence of chronic diseases (2 on average), while the lonely and single living spouses had an average of 3
diseases. The deficiencies of the patronage service are revealed, which may be due to the lack of standards for individual
nosologies. The inconsistency in the provision of medical and social assistance was also identified. Conclusions: the
lack of national standards for the management of elderly patients, taking into account the presence of several chronic
diseases and the provision of medical and social care at the primary level, insufficient time for taking a doctor, the lack
of integration of medical and social care reduces the quality of medical care provided to the elderly population

R.T. Kamilova — 2020-07-16

Sanitary-hygienic assessment of the conditions of education in educational institutions, the
determination of their compliance with established sanitary and hygienic standards. Materials and methods: The
studies were conducted in general education schools located in Mirzo Ulugbek, Yunusabad, Shayhantakhur districts
of Tashkent city. Results: In primary schools of the Mirzo-Ulugbek district, the actual number of students exceeded
the estimated number by the project by 9.8%, and in schools of Shaykhantakhur and Yunusabad districts - by 10%,
water supply system malfunction (internal, external), defective sanitary equipment, non-fulfillment rules of student
seating, insufficient natural lighting of the premises is confirmed by KEO values, which were in the range of 0.7 to 1%
at a hygienic rate of 1.5%. Conclusions: In all surveyed of primary schools, the actual number of students exceeded
the estimated number by an average of 10%; insufficient equipment was observed for sports equipment, water supply
disruptions, the provision of non-rational student furniture, and violation of indoor light conditions

HYGIENIC ASSESSMENT OF THE CONDITIONS OF EDUCATION IN THE PREPARATORY GROUPS OF PRESCHOOL INSTITUTIONS

N.F. Khusanova — 2020-07-16

an objective hygienic assessment of the conditions of training and education in children’s educational
institutions using new approaches. Material and methods: the main factors determining the hygienic state of preschool
educational institutions were the land plot, the building, the sanitary equipment and its condition, the educational process.
Each of these factors contains from 5 to 12 significant indicators. The following criteria were used to quantify each
indicator: good - meets the hygienic rate of 100%; satisfactory - compliance at 70-89.9%; unsatisfactory - compliance by
50-69.9%. Results: thanks to the use of an improved method of assessing the state of children’s educational institutions,
an objective quantitative and qualitative characteristic of each factor will be obtained, which will enable us to make an
operational decision to manage risk factors aimed at promoting the health of young children.

THE ROLE OF GENE POLYMORPHISM OF NEUROHUMORAL FACTORS IN THE DEVELOPMENT OF CHRONIC HEART FAILURE

A.G. Gadayev — 2020-07-16

The latest data on the representatives identification of complex genes with various phenotypes of chronic heart
failure are given. Both the role of gene polymorphism in the disease pathogenesis of the choice of recommended drugs, the
provision of high-quality prophylaxis and also in the prevention of adverse outcomes of the disease has been substantiated

THE CURRENT STATE OF THE PROBLEM OF LIPID PEROXIDATION

B.U. Iriskulov — 2020-07-16

This article assesses the state of the problem of lipid peroxidation. Free radical processes are highly reactive and
are essential components of the normal functioning of cells. Are known radicals of hydrogen peroxide, hydroxyl,
superoxide radicals and singlet oxygen. To the formation of a radical anion of oxygen and hydrogen peroxide leads to
a “respiratory explosion” (an increase in the consumption of oxygen by neutrophils, macrophages, etc.). In peroxisome
oxidases, oxygen is restored to hydrogen peroxide (urotoxicity, glycolate oxidase, L-amino acid oxidase). These radicals
and active oxygen species (ROS) have a bactericidal effect.

THE VALUE OF BIOLOGICAL MARKERS IN THE DIAGNOSIS, PREDICTION AND EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF CHRONIC HEART FAILURE

A.K. Kurbonov — 2020-07-16

BRONCHIAL ASTHMA IN CHILDREN: A MODERN VIEW OF THE PROBLEM

M.H. Mirrahimova — 2020-07-16

Bronchial asthma is one of the most common chronic diseases. Statistical indicators of the prevalence of asthma
are based mainly on data obtained from the treatment of patients in medical institutions. However, information on the
prevalence of bronchial asthma does not correspond to reality, as many patients for various reasons do not address to
medical institutions. The parents of the children have a negative attitude towards diagnosing a chronic disease, and
doctors often do not diagnose bronchial asthma, especially in the early stages of development and in cases of mild diseases.
Thus, according to the Healthcare data of the Tashkent region, a number of patients, especially those with mild bronchial
asthma, did not establish the correct diagnosis at all in the childhood period, and in a significant proportion of patients
with moderate and severe asthma, the correct diagnosis was made with a delay of 2-6 years from the onset of the disease.

B.D. Babadjanov — 2020-07-16

To study the effectiveness of minimally invasive endovascular methods in the treatment of diabetic gangrene of
the lower extremities, depending on the risk of loss of the limb. Material and methods: the results of inpatient treatment of
323 patients (225 (69.6%) men and 98 (30.4%) women) with surgical complications of diabetic foot syndrome who were in
2012-2018 were analyzed. at the Republican Center for purulent surgery and surgical complications of diabetes mellitus at the
2nd TMA clinic. All patients suffered from type 2 diabetes. 203 patients were given insulin to correct their blood sugar levels.
The neuroischemic form of diabetic foot syndrome was diagnosed in 271 (83.9%) patients, ischemic - in 52 (16.1%) patients.
Results: large ulcerative defects (W3) were observed in 123 (38.1%) patients, an average degree (W2) of the wound process
occurred in 136 (42.1%), a superficial wound defect (W1) in 43 (13.3%). Severe ischemia (I3) of the limb was diagnosed in 76
(23.5%) patients, moderate ischemia (I2) in 135 (41.8%), and light ischemia in 112 (34.6%). Conclusions: long-term intraarterial
catheter therapy in patients with diabetic gangrene of the lower limb with a high risk of it after complete balloon
angioplasty increases the chance of maintaining the limb support function up to 88.7%. The use of a complex of minimally
invasive X-ray endovascular methods for treating lower extremity diabetic gangrene, even in patients with a high risk of limb
loss (77-94% wifi), can reduce the frequency of hip amputation from 12.6 to 8.0% and reduce mortality from 5.7 to 3, 2%.

Z.A. Giyasov — 2020-07-16

A comprehensive analysis of medical care defects (MCD) on the materials of the CFME. Material and
methods: The object of the study was the materials of the CFME conducted in the Tashkent Regional Bureau of Forensic
Medical Examination in 2016-2017. In total, during this period, 51 (38) examinations were conducted about the inadequate
provision of medical care to children and adolescents, which accounted for 31.3% of the total number of CFME. The analysis
of the obtained results was carried out using comparative, logical and statistical research methods. Results: In total, 52
MCD were verified, since in 11 cases two or more defects were identified. When analyzing the age structure of the patients,
it was found that the majority were children under the age of 1 year (55.3%) and 1-3 years (21.1%). 39 (76.5%) defects had
a significant impact on the outcome. Moreover, 34 of them, aggravating the condition of children, contributed to the onset
of death. More than half of MCD admitted to inpatient medical institutions. About 80% of MCD occur for subjective reasons
- due to lack of qualifications or inattention to the patient and have a significant impact on the outcome.

EVALUATION OF QUALITY OF LIFE OF PATIENTS WITH LIVER CIRRHOSIS AFTER PORTOSYSTEMIC SHUNTING DEPENDING ON COMPLIANCE OF POSTOPERATIVE RECOMMENDATIONS

A.V. Devyatov — 2020-07-16

assessment of the quality of life of patients with cirrhosis after portosystemic shunting (PSS) depending
on compliance with postoperative recommendations. Material and Methods: the quality of life analysis was carried out
in 490 patients with cirrhosis of the liver after PSS. Long-term results were followed up in 385 patients. The average
age of patients at the time of surgery was 29.7 ± 0.7 years. To assess the quality of life, a special questionnaire developed
by Z.M. Younossi et al. (1999), visual analogue scales. Results: after PSS, the survival rate of patients and their quality
of life directly depended on the severity of the pathological process in the liver. Refusal or irregular examination and
specific conservative therapy led to a significant decrease in the quality of life index after PSS: physical decline to
3.4 ± 0.2 points versus 4.5 ± 0.7 points, on a physical condition scale to 49.2 ± 5 , 1%, according to - 65.1 ± 5.1%.
Conclusions: In patients with portal hypertension in the absence of a risk of developing hemorrhagic syndrome after
PSS, regular follow-up examinations and conducting courses of conservative therapy for the prevention or treatment
of other complications of liver cirrhosis CP are of fundamental importance.

STUDYING THE STRATEGIES OF BEHAVIOR IN PATIENTS WITH PULMONARY TUBERCULOSIS WITH MULTIPLE DOSING STABILITY AND LOW AGREEMENT TO TREATMENT

M.Kh. Djurabaeva — 2020-07-16

To study the emotional, motivational, and cognitive components of the relationship to the disease in
patients with pulmonary tuberculosis with multidrug resistance (MDR / TB of the lungs). Material and Methods: 32
patients with multidrug-resistant pulmonary tuberculosis who received a standard chemotherapy regimen with backup
anti-TB drugs were supervised. The object of empirical research is 72 people (42 women and 30 men), who were divided
into 3 groups: Group 1 (control) - 40 people without somatic diseases, Group 2 - 18 newly diagnosed patients with
MDR / TB lungs, 3rd group - 14 re-treated patients with MDR / TB of the lungs. Results: as the observations showed,
patients with drug-resistant pulmonary tuberculosis tend to exhibit non-positive emotional reactions, resorting to
aggressive communication strategies, while after a step-by-step retesting program, an increase in compliance and
long-term treatment was observed. Conclusions: according to the results of the study, a step-by-step program of work
with patients with MDR / TB of the lungs who have difficulties in social adaptation has been developed.

THE USE OF LOCAL LEGUMES IN THE DIET THERAPY OF CHRONIC HEPATITIS

S.Y. Zokirkhodjayev — 2020-07-16

the possibility of using in soups of chronic hepatitis soups from local bean products prepared using the
new technology, and evaluating their effectiveness. Material and methods: studies were conducted on 47 patients
with chronic hepatitis who were treated in the 2nd therapeutic department of the 1st TMA clinic. They were divided
into 2 groups: the 1st one - the usual diet therapy, the 2nd one - with the Parhez Mohor diet therapy prepared from local
beans. Results: In the period of exacerbation of chronic hepatitis, the clinical picture, laboratory and instrumental
parameters change according to the severity of the disease. The use of the “Parhez Mohora” dish, prepared on the
basis of the new technology, as a dietary therapy, had a positive effect on the dynamics of the disease, manifested by a
significant improvement in the enzyme spectrum of the blood serum and normalization of hematological parameters.
This is due to specific vegetable proteins, the content of polyunsaturated fatty acids, carbohydrates in the form of
starch, mono- and disaccharides, as well as a high content of vitamins of group B, E, C, PP.

S.I. Indiaminov — 2020-07-16

The study of the nature and characteristics of the course of mechanical damage of the complex larynx for the tasks of
forensic medical examination. Materials and methods: On the material of expertise special methods were investigated 12 cases on
injured complex of larynx, occurring on variety types of enforced death. Results: in general, the mechanisms of formation of injuries
of the hyoid bone, thyroid cartilage and cricoid cartilage from compression of the neck by a loop and due to mechanical injury are
similar, since the localization and nature of fractures depends on which direction the compression occurs. Conclusion: There was
established that the whole mechanisms injury formation of subglossal bone, thyroid cartilage and annular cartilage from prelum
cervix loop and mechanical traumas analogous between each other, in that being localization and character fractures depending
on that directions where occurs pressure. It is marked, during analyzing injured complex of larynx allows not only fractographical
properties, localization and capacity of determined fractures, but also type, directions and mechanism actions of traumatic agency,
as well as presence of anatomical particularity changes occurring owing to early carried trauma.

IMPROPER MEDICAL ASSISTANCE IN ACTIVITIES OBSTETRICIANS-GYNECOLOGISTS

Sh.E. Islamov — 2020-07-16

to determine the nature of defects in medical care in the activities of obstetrician-gynecologists.
Materials and methods: According to a special computer program using the card-questionnaires developed by
us, 2,890 findings of the instrumental medical examination commissioned by obstetrician-gynecologists regarding
professional offenses conducted in all forensic institutions of the Republic of Uzbekistan from 1999 to 2010 were
studied. Results: In the activities of obstetrician-gynecologists, DMA were more frequently observed in Navoi (39.3%),
Tashkent (31.4%), Andijan (31.2%), Syrdarya (30.6%) and Bukhara (30%) regions. Among the defects of diagnosis
prevail non-recognition of the underlying disease and its complications. Defects of treatment were identified in the
form of errors in the appointment and conduct of medical procedures (including irrational management of labor),
defects in surgical treatment, defects in medical treatment. Conclusions: In the activities of obstetrician-gynecologists
by the nature of the DMA, there is a predominance of defects in treatment and diagnosis

M.YU Karimov — 2020-07-16

APPLICATION OF APR-01 M “MEDNORD PIEZOELECTRIC THROMBOPLASTOGRAPH IN PREGNANT WOMEN WITH HYPERTENSIVE DISORDERS

Sh.S. Muhamedova — 2020-07-16

Determination with the method Thromboelastography of the global coagulation of pregnant women blood
of with hypertensive disorders. Material and methods: We studied 40 pregnant women with hypertensive syndrome and
aggravated obstetric history of hospitalization patients. The studies were conducted in the clinic of Republican Center
of obstetrics and Gynecology of the Ministry of Health of the Republic of Uzbekistan. The state of the blood coagulation
system was studied using an APR-01 M “MEDNORD” piezoelectric thromboelastograph (Russia). Results: Variations in
the hemostatic potential depending on the trimester of pregnancy were revealed: in the first trimester, chronometric
hypercoagulation is observed, in the second, chronometric hypocoagulation is observed, in the third - a hypercoagulative
shift at the proteolytic stage, with chronometric hypocoagulation at the stages of polymerization and clot stabilization.
Conclusions: With ARP-01M Mednord piezoelectric thromblastograph (PTEG), it is possible to determine 18 parameters
of the hemostasis system at any time of the day without additional use of reagents.

ALGORITHM OF ENDOSCOPIC SURGERY OF CORAL SHAPED STONES AND MULTIPLE NEPHROLITHIASIS

Sh.T. Mukhtarov — 2020-07-16

To optimize a tactics of endoscopic surgery for staghorn nephrolithiasis and increase a treatment
efficacy of nephrolithiasis. Materials and methods: 158 patients with coral shaped stones nephrolithiasis have been
investigated and treated. Results: Using an algorithm of endoscopic surgery for coral shaped stones nephrolithiasis
have leaded to increase a stone clearance rate up to 90,0%. Conclusion: It is concluded that including an algorithm of
endoscopic surgery for coral shaped stones nephrolithiasis in the investigation and treatment have leaded to increase
and efficacy of treatment of nephrolithiasis.

SHORT-TERM OUTCOMES OF LAPAROSCOPIC REMOVAL OF OVARIAN CYSTS IN PATIENTS WITH INFERTILITY USING VARIOUS METHODS OF SURGICAL HEMOSTASIS

D.K Najmutdinova — 2020-07-16

to study the short-term outcomes of laparoscopic removal of ovarian cysts using different methods of
hemostasis (closure, monopolar, bipolar and ultrasound coagulation) in infertility patients. Material and methods:
The prospective part of the study included 8 patients with ovarian cysts and infertility, who were operated on
laparoscopically in the period from May to September 2018 under conditions of the Department of Gynecology No. 1
of the State Administration of the RSNPMTSAG. Retrospectively, the same criteria were analyzed in 32 patients with
infertility, who in the period from 2017 to 2018. laparoscopic removal of ovarian cysts was performed. Results: The use of
a combination of mechanical and systemic chemical hemostasis during laparoscopic removal of ovarian cysts in women
with infertility does not lead to an increase in the duration of surgical treatment and the volume of intraoperative blood
loss. The combination of laparoscopic suturing of the bleeding areas of the bed of the removed cyst with intravenous
administration of tranexamic acid does not worsen the course of the postoperative period and does not increase the
duration of hospitalization. The use of a combination of mechanical and chemical hemostasis in laparoscopic removal
of ovarian cysts in patients with infertility is a good alternative to conventional and widely used methods of hemostasis.
Conclusions: it is necessary to conduct further studies to assess the effect of various methods of hemostasis on the ovarian
reserve and reproductive outcomes in patients with infertility who underwent laparoscopic removal of ovarian cysts.

SHORT-TERM OUTCOME OF LAPAROTOMIC MYOMECTOMY WITH TRANSIENT UTERINE VESSELS OCCLUSION IN INFERTILE PATIENT

D.K. Najmutdinova — 2020-07-16

To evaluate the effectiveness of myomectomy with intraoperative temporary ligation of uterine vessels in patients
with infertility. Material and methods: the study included data from 61 patients suffering from a combination of infertility and
uterine fibroids, who required surgical treatment. All patients were operated on at the Department of Gynecology No. 1 of the State
Administration of the Republican Specialized Scientific Center of Obstetrics and Gynecology in 2015-2018. The data of 43 retrospective
analyzed patients who underwent myomectomy underwent a permanent uterus ligation procedure and 7 patients who underwent
uterus ligation during myomectomy were not analyzed at all. The prospective part of the study included data from 11 patients who
underwent a temporary ligation of the uterine vessels when performing myomectomy. Results: temporary ligation of uterine vessels
during myomectomy has a beneficial effect on short-term surgical outcomes, such as intraoperative blood loss, hemoglobin blood
in the blood, periods of recovery of bowel function, the need for analgesics, as well as discharge periods after surgery. The positive
effect in patients with temporary ligation of the uterine vessels is manifested to a greater extent than in patients with permanent.
Conclusions: for a comprehensive study of the place of temporary ligation of the uterine vessels when performing myomectomy,
women with infertility should conduct further research to assess long-term (reproductive and ovarian) outcomes.

FEATURES OF INTRAOPERATIVE ADMINISTRATION OF ANTIBACTERIAL DRUGS FOR HIP JOINT ARTHROPLASTY IN PATIENTS WITH TUBERCULOSIS COXITIS

F.Kh. Rustamov — 2020-07-16

to improve the results of hip arthroplasty in patients with tuberculous coxitis by developing measures
to prevent suppurative septic complications. Material and methods: in order to develop measures for the prevention
of septic complications, treatment outcomes were studied in 60 patients with tuberculosis coxitis, who were
performed hip joint arthroplasty operations in the clinic of Republican Scientific Research Center of Phthisiology and
Pulmonology in 2014-2018. Results: in all patients who underwent antibacterial therapy according to the proposed
method, primary healing of postoperative wound was noted, postoperative complications were not observed. It was
also found that, despite the high doses of the antibiotic, its concentration after a threefold administration decreases, to
maintain the required level, its additional administration is required up to 6 times.Conclusions: The six-time antibiotic
administration scheme developed by the authors maintains the therapeutic concentration of the drug in the blood and,
therefore, prevents the development of paraprosthetic complications.

CLINICAL TESTS TO EVALUATE THROMBUS RETRACTION TO FORM A BIOCOATING

R.A. Sadykov — 2020-07-16

EARLY AND LATE COMPLICATIONS OF SURGICAL TREATMENT OF TRAUMATIC INTRACRANIAL HEMATOMAS

Sh.M. Kariev — 2020-07-16

assessment of early and late complications after surgical treatment of patients with traumatic intracranial
hematomas. Material and methods: 342 patients with traumatic intracranial hematomas were under our control in
Republican Specialized Scientific Practical Medical Center of Neurosurgery. Decompressive craniotomy was performed in
222 (64.9%) patients, osteoplastic craniotomy in 120 (35.1%) patients. Results: Postoperative complications were observed
in 28% of patients with traumatic intracranial hematomas who underwent decompressive craniotomy and 23% after
osteoplastic craniotomy. The most frequent were purulent-inflammatory complications resulted penetrating traumatic
brain injury factors extensive wounds of the soft covers of the skull, reducing the immunological protective properties of the
body, infection Liquorodynamic complications in the form of dysresorptive hydrocephalus (1.4%) and subdural hydroma
(4.1%) were more often observed after decompressive craniotomy. Conclusions: A large number of purulent-inflammatory
complications were caused by a combination of many factors: the presence of penetrating traumatic brain injury in some
patients, extensive wounds of the soft covers of the skull, reduced immunological protective properties of the body in response
to injury, the development of systemic inflammatory syndrome, the addition of nosocomial infection

SURGICAL TREATMENT OF POSTOPERATIVE INTRAPLEURAL BLEEDING

Sh.N. Hudaybergenov — 2020-07-16

to improve the tactics of postoperative treatment of intrapleural bleeding. Material and methods:
analyzed the results of treatment of 334 patients with postoperative intrapleural complications, operated on at the
Central State Clinical Hospital at the Regional Clinical Hospital No. 1 named after. prof. S.V. Ochapovsky (Krasnodar) in
2003-2008 and in the department of surgery of the lungs and mediastinum of the RSCS named. Acad. V. Vakhidov in 1999-
2018. The tactics of management of patients with intrapleural complications differed in the range of new technologies
implementation. Results: postoperative bleeding was observed in 123 patients, including 72 (58.53%) with intrapleural
bleeding, 39 (31.7%) with coagulated hemothorax, and 12 (9.7%) with parietal hematoma. 67 patients were operated
on the 1 st day after the development of the complication, satisfactory results were observed in 66 (98.5%) of them, an
attempt to conservative hemostasis and repeated intervention on the 2nd day increased the number of unsatisfactory
results by almost 4 times , 5 to 5.6%. Conclusion: Minimally invasive interventions have several advantages in eliminating
postoperative intrapleural hemorrhages: low invasiveness, reduce the length of stay of patients in the hospital and thereby
reduce the material costs. The use of PTS in coagulated hemothoraxes is the method of choice.

OPTIMIZATION OF MANAGEMENT OF HYPERTENSIVE STATES IN PREGNANT WOMEN WITH THE USE OF INPATIENT MHEALTH REPLACEMENT TECHNOLOGIES

R.B. Yusupbaev — 2020-07-16

Development and study of the effectiveness of new hospital replacing mHealth technologies in pregnant
women with hypertensive disorders. Material and methods: We studied 40 pregnant women with hypertensive
syndrome and aggravated obstetric history of hospitalization patients. The studies were conducted in the clinic of
RSSPMCOaG and the Ministry of Health of the Republic of Uzbekistan. Patient’s monitor using “TRITON Electronics
MPR 6-03” apparatus, “Angioscan” device application. Results: in the 1st group, 40% of women had a full-term birth,
in the 2nd - 70%. In the 1st group, preterm labor was observed in 60% of cases, in the 2nd - in 30%, since 2 times
less. Operative delivery in the 1st group had to be resorted to in 90% of patients. Conclusions: analysis of the type of
waves received on the device “Angioskan”, showed that the type of wave A is one of the markers of contraindications to
mHealth, therefore, further examination of pregnant women in stationary conditions is necessary.