CLINICAL AND EPIDEMIOLOGICAL STUDY OF MOTOR NEURON DISEASE

Abstract

According to worldwide data, the average incidence of motor neuron disease (MND) is approximately 0.2–2.4 cases per 100,000 population. However, despite the relative rarity of this disease, its medical and social significance is extremely high: motor neuron disease is an incurable, disabling disease with a high incidence of lesions in people of working age, inevitably leading to death. The disease is based on the combined progressive degeneration of upper and lower motor neurons, which is clinically manifested by a combination of signs of central and peripheral paralysis. The etiology and pathogenesis of the disease remain not fully studied.