HEMODYNAMIC STATUS AND EFFICACY OF THE DRUG "EDARAVON" IN ACUTE AND CHRONIC DISORDERS OF CEREBRAL CIRCULATION

Abstract

Background. The article presents the results of an open longitudinal study of two parallel groups, in which the effect of the drug Edaravon on the clinical course of acute ischemic stroke and secondary hemodynamic effects were studied.

Material and methods. Group 1 patients (n=20) received traditional therapy for ischemic stroke and Group 2 patients (n=20) received Edaravon 2 times a day and traditional therapy for ischemic stroke for 10 days.

The results showed that adding Edaravon to conventional therapy for ischemic stroke effectively reduced cerebral oedema, which plays an important role in the processes of early and late neuronal damage.

Conclusion. Treatment contributed to a significant improvement in the clinical course of the disease, a rapid reduction of the perifocal oedema zone, which was confirmed by the reduction of neurological deficit, according to clinical scales and the results of dopplerography.