THE RATIONALE FOR THE CHOICE OF ANTISEPTICS IN THE TREATMENT OF OSTEOARTICULAR PURULENT INFECTION

Authors

  • A.O. Okhunov Tashkent Medical Academy

Keywords:

Purulent infection, antiseptics, local treatment of purulent wounds

Abstract

Polymeric antiseptics from the group of polyhexamethylene guanidines prevent the formation of microbial biofilms and have an antitoxic effect. These antiseptics, including in combination with complexesfrom the bisphosphonate group and Unitiol, inhibit metallo-beta-lactamase and beta-lactamase of multidrug-resistant gram-negative bacteria while enhancing the effect of carbapenems and cephalosporins. The composition based on high-molecular-weight polyvinylpyrrolidone, amikacin and dioxidine has a prolonged effect, antitoxic properties, the ability to localize the infectious focus and impart antimicrobial activity to the tissues surrounding the wound. 

Author Biography

A.O. Okhunov, Tashkent Medical Academy

Professor, DM, PhD, Head of the Department of General and Pediatric Surgery of the Tashkent Medical Academy, foreign member of the US Surgical Infection Societies (SIS) and Europe (SIS-E), member of the International Federation Surgery of Obesity (IFSO), Tashkent, Uzbekistan

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Published

2023-10-30

How to Cite

Okhunov, A. (2023). THE RATIONALE FOR THE CHOICE OF ANTISEPTICS IN THE TREATMENT OF OSTEOARTICULAR PURULENT INFECTION. JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE, 2(3), 109-112. Retrieved from https://mail.journals.tma.uz/index.php/jesm/article/view/644

Issue

Vol. 2 No. 3 (2023): JESM 2023 #3 (Vol.2)

Section

Articles

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